Biostatistics 666: Analysis of Copy Number Using Sequence Data

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Overview

Introduces the analysis of copy number variation using next generation sequence data, discussing the types of evidence that can be observed in one individual and also in a population of individuals where a copy number variant is segregating.

Slides

Slides in PDF Format

Recommended Reading

  • Handsaker, Korn, Nemesh and McCarroll (2011) Discovery and genotyping of genome structural polymorphism by sequencing on a population scale. Nature Genetics 43:269 - 276
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