SplitPed

This page documents the splitPed program, which splits a pedigree file into smaller files with subsets of markers.

Input Files

Required Input Files

Pedigree file

File fed to -ped option, in Merlin format pedigree file. For details of the Merlin file format, see the Merlin tutorial [1].

Within each file, markers should be stored by chromosome position. Alleles should be stored in the forward strand and can be encoded as 'A', 'C', 'G' or 'T' (there is no need to use numeric identifiers for each allele).

Marker information file

File fed to -dat option, in Merlin format marker information file. For details of the Merlin file format, see the Merlin tutorial [2].

Optional Input Files

Map file

File fed to -map option, containing chromosome, marker name, and marker coordinate (in base pairs) information for each marker. Markers should be stored in the same order as in the marker information file.

Options

Required options

window size

Window size can be specified by one of the following three options: (1) -nWindows (2) -windowSize and (3) -windowLength.

-nWindows specifies the number of windows to split into and the program splits markers evenly into output windows.

-windowSize specifies the number of markers in one output window. The remainder goes to the last window.

-windowLength specifies the length (in base pairs) of one output window. The remainder goes to the last window. Note that this option is only allowed when map input file is specified.

flanking region

Size of flanking region on each side can be specified by one of the following two options: (1) -overlapSize and (2) -overlapLength.

-overlapSize specifies the number of markers in each flanking region (so that the total number of flanking markers for each window is twice the number specified except for the first and last window).

-overlapLength specifies the length (in base pairs) of each flanking region (so that the total length of the flanking regions is twice the number specified except for the first and last window).

Questions and Comments?

Email Yun Li.