830 - Haplotyper::ImputeGenotypes() (internal)
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Jump to navigationJump to searchvoid Haplotyper::ImputeGenotypes(float * matrix1, float * matrix2, int marker)
{
posterior[0][marker] = posterior[1][marker] = posterior[2][marker] = 0.0;
for (int i = 0; i < states; i++, matrix1++, matrix2++)
{
if (haplotypes[i][marker])
for (int j = 0; j < i; j++, matrix1++, matrix2++)
posterior[haplotypes[j][marker] + 1][marker] += *matrix1 * *matrix2 * 0.5;
else
for (int j = 0; j < i; j++, matrix1++, matrix2++)
posterior[haplotypes[j][marker]][marker] += *matrix1 * *matrix2 * 0.5;
posterior[haplotypes[i][marker] * 2][marker] += *matrix1 * *matrix2;
}
double sum = posterior[0][marker] + posterior[1][marker] + posterior[2][marker];
posterior[0][marker] /= sum;
posterior[1][marker] /= sum;
posterior[2][marker] /= sum;
}