Biostatistics 666: Applications of the Lander-Green Algorithm

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Outline

This lecture outlines three useful applications of the inheritance vector concept that was first introduced in the Lander-Green algorithm. The applications are the calculation of parametric and non-parametric linkage statistics, and information content calculations.

Class Notes

Slides in PDF Format

References

Kruglyak, Daly, Reeve-Daly and Lander (1996) Am J Hum Genet 58:1347-63

Kong and Cox (1997) Am J Hum Genet 61:1179-88

McPeek (1999) Genetic Epidemiology 16:225–249

Whittemore and Halpern (1994) Biometrics 50:118-27.