Biostatistics 666: Contemporary Human Genetics

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Objective

This lecture introduces course objectives, which are to provide students with a working understanding of the techniques commonly used by statistical geneticists. These techniques can serve as building blocks for the implementation of more complex, customized analyses. In addition, the lecture provides a brief overview of modern human genetics trying to introduce the idea of rapidly increasing data sizes and the opportunities and challenges posed by modern GWAS.

Recommended Reading

If you need a refresher or introduction to molecular genetics, I recommend:

Human Molecular Genetics by Tom Strachan and Andrew Read Web Edition at NCBI

Lander and Schork (1994) "Genetic Dissection of Complex Traits" Science 265:2037-48 PDF at Science Magazine

Slides

Slides in PDF Format