Gene Ontology
Gene Ontology is a structured annotation of genes that encodes information about their biological function. It is a useful aid when interpreting results of micro-array studies and other studies that might identify large numbers of potentially interesting genes.
Examples
In 2005, Smith and colleagues [1] examined whether genes in regions of extended linkage disequilibrium were systematically different from those in regions with more limited linkage disequilibrium. They found that certain genes (such as those involved in cell cycle regulation and response to DNA damage) were enriched in regions of strong linkage disequilibrium, whereas others (such as genes involved in immune response) were enriched in regions with more limited linkage disequilibrium.
External Link
Go to www.geneontology.org.
For an annotated list of genes, download the file gene_assoaciation.goa_human.gz
References
- ↑ Smith AV, Thomas DJ, Munro HM and Abecasis GR (2005). Sequence features in regions of weak and strong linkage disequilibrium. Genome Res 15:1519-34
