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	<id>http://genome.sph.umich.edu/w/index.php?action=history&amp;feed=atom&amp;title=Biostatistics_666%3A_Linkage_Analysis_in_Sibling_Pairs</id>
	<title>Biostatistics 666: Linkage Analysis in Sibling Pairs - Revision history</title>
	<link rel="self" type="application/atom+xml" href="http://genome.sph.umich.edu/w/index.php?action=history&amp;feed=atom&amp;title=Biostatistics_666%3A_Linkage_Analysis_in_Sibling_Pairs"/>
	<link rel="alternate" type="text/html" href="http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;action=history"/>
	<updated>2026-09-26T12:08:20Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=14951&amp;oldid=prev</id>
		<title>Goncalo: /* Slides */</title>
		<link rel="alternate" type="text/html" href="http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=14951&amp;oldid=prev"/>
		<updated>2017-11-15T13:30:49Z</updated>

		<summary type="html">&lt;p&gt;&lt;span class=&quot;autocomment&quot;&gt;Slides&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 09:30, 15 November 2017&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l5&quot;&gt;Line 5:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Slides ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Slides ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Media:666.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;2010&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;02&lt;/del&gt;.pdf|Slides in PDF Format]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Media:666.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;2017&lt;/ins&gt;.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;14_-_Affected_Sibling_Pairs&lt;/ins&gt;.pdf|Slides in PDF Format]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Recommended Reading ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Recommended Reading ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Goncalo</name></author>
	</entry>
	<entry>
		<id>http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=5631&amp;oldid=prev</id>
		<title>Goncalo: /* Recommended Reading */</title>
		<link rel="alternate" type="text/html" href="http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=5631&amp;oldid=prev"/>
		<updated>2012-10-29T06:08:53Z</updated>

		<summary type="html">&lt;p&gt;&lt;span class=&quot;autocomment&quot;&gt;Recommended Reading&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 02:08, 29 October 2012&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l13&quot;&gt;Line 13:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 13:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Risch (1990) Linkage strategies for genetically complex traits. I. Multi-locus models. &amp;#039;&amp;#039;Am J Hum Genet&amp;#039;&amp;#039; &amp;#039;&amp;#039;&amp;#039;46&amp;#039;&amp;#039;&amp;#039;:222-228&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Risch (1990) Linkage strategies for genetically complex traits. I. Multi-locus models. &amp;#039;&amp;#039;Am J Hum Genet&amp;#039;&amp;#039; &amp;#039;&amp;#039;&amp;#039;46&amp;#039;&amp;#039;&amp;#039;:222-228&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Holmans (1993) Asymptotic Properties of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;�Affected&lt;/del&gt;-Sib-Pair Linkage Analysis. &#039;&#039;Am J Hum Genet&#039;&#039; &#039;&#039;&#039;52&#039;&#039;&#039;:362-374&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Holmans (1993) Asymptotic Properties of &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Affected&lt;/ins&gt;-Sib-Pair Linkage Analysis. &#039;&#039;Am J Hum Genet&#039;&#039; &#039;&#039;&#039;52&#039;&#039;&#039;:362-374&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Goncalo</name></author>
	</entry>
	<entry>
		<id>http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=2466&amp;oldid=prev</id>
		<title>Goncalo: /* Slides */</title>
		<link rel="alternate" type="text/html" href="http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=2466&amp;oldid=prev"/>
		<updated>2010-11-11T07:08:28Z</updated>

		<summary type="html">&lt;p&gt;&lt;span class=&quot;autocomment&quot;&gt;Slides&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 03:08, 11 November 2010&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l5&quot;&gt;Line 5:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Slides ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Slides ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[666.2010.02.pdf|Slides in PDF Format]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Media:&lt;/ins&gt;666.2010.02.pdf|Slides in PDF Format]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Recommended Reading ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Recommended Reading ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Goncalo</name></author>
	</entry>
	<entry>
		<id>http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=2465&amp;oldid=prev</id>
		<title>Goncalo: Created page with &#039;== Outline ==  This lecture introduces Neil Risch&#039;s Maximum Lod Score (MLS) test for linkage and its refinement using Peter Holman&#039;s possible triangle constraint.  == Slides ==  …&#039;</title>
		<link rel="alternate" type="text/html" href="http://genome.sph.umich.edu/w/index.php?title=Biostatistics_666:_Linkage_Analysis_in_Sibling_Pairs&amp;diff=2465&amp;oldid=prev"/>
		<updated>2010-11-11T07:08:07Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;#039;== Outline ==  This lecture introduces Neil Risch&amp;#039;s Maximum Lod Score (MLS) test for linkage and its refinement using Peter Holman&amp;#039;s possible triangle constraint.  == Slides ==  …&amp;#039;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== Outline ==&lt;br /&gt;
&lt;br /&gt;
This lecture introduces Neil Risch&amp;#039;s Maximum Lod Score (MLS) test for linkage and its refinement using Peter Holman&amp;#039;s possible triangle constraint.&lt;br /&gt;
&lt;br /&gt;
== Slides ==&lt;br /&gt;
&lt;br /&gt;
[[666.2010.02.pdf|Slides in PDF Format]]&lt;br /&gt;
&lt;br /&gt;
== Recommended Reading ==&lt;br /&gt;
&lt;br /&gt;
Risch (1990) Linkage Strategies for Genetically Complex Traits. III. The Effect of Marker Polymorphism on Analysis of Affected Relative Pairs. &amp;#039;&amp;#039;Am J Hum Genet&amp;#039;&amp;#039; &amp;#039;&amp;#039;&amp;#039;46&amp;#039;&amp;#039;&amp;#039;:242-253&lt;br /&gt;
&lt;br /&gt;
Risch (1990) Linkage strategies for genetically complex traits. I. Multi-locus models. &amp;#039;&amp;#039;Am J Hum Genet&amp;#039;&amp;#039; &amp;#039;&amp;#039;&amp;#039;46&amp;#039;&amp;#039;&amp;#039;:222-228&lt;br /&gt;
&lt;br /&gt;
Holmans (1993) Asymptotic Properties of �Affected-Sib-Pair Linkage Analysis. &amp;#039;&amp;#039;Am J Hum Genet&amp;#039;&amp;#039; &amp;#039;&amp;#039;&amp;#039;52&amp;#039;&amp;#039;&amp;#039;:362-374&lt;/div&gt;</summary>
		<author><name>Goncalo</name></author>
	</entry>
</feed>