MaCH: Difference between revisions
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'''MaCH''' (MArkov Chain Haplotyping) is a | '''MaCH''' (MArkov Chain Haplotyping) is a Hidden Markov Model (HMM) based haplotyper that reconstructs haplotypes from genotypes of unrelated individuals. Three primary utilities of MaCH are (1) to resolve haplotypes from diploid genotypes; (2) impute missing genotypes; and (3) perform disease mapping analysis. | ||
== Options == | == Options == | ||
Input Files: | |||
--datfile | |||
Marker information file as described in section 3. | |||
--pedfile | |||
Pedigree file as described in section 3. | |||
== FAQ == | == FAQ == | ||
Revision as of 17:26, 26 April 2010
MaCH (MArkov Chain Haplotyping) is a Hidden Markov Model (HMM) based haplotyper that reconstructs haplotypes from genotypes of unrelated individuals. Three primary utilities of MaCH are (1) to resolve haplotypes from diploid genotypes; (2) impute missing genotypes; and (3) perform disease mapping analysis.
Options
Input Files: --datfile Marker information file as described in section 3. --pedfile Pedigree file as described in section 3.
