Biostatistics 666: Advanced Coalescent, Computation with the Coalescent
Guest Lecturer
This will be a guest lecture by Sebastian Zoellner, who is our department's resident expert on the coalescent.s
Objective
Provide an introduction to computational methods that are used, together with the coalescent, to study the properties of particular populations based on a set of coalescent models.
Slides
Recommended Reading
Richard R. Hudson (1990) Gene genealogies and the coalescent process in Oxford Surveys in Evolutionary Biology (vol. 7). Edited by D. Futuyma and J. Antonovics. Published by Oxford University Press, New York.
Marjoram P and Tavare S (2006) Modern computational approaches for analysing molecular genetic variation data. Nature Reviews Genetics 7:759-770
Schaffner SF, Foo C, Gabriel S, Reich D, Daly MJ and Altshuler D (2005) Calibrating a coalescent simulation of human genome sequence. Genome Research 15:1576-83