View source for Biostatistics 666: Hardy-Weinberg Equilibrium

== Objective ==

The objective of this lecture is to introduce the concept of Hardy Weinberg equilibrium. Hardy Weinberg equilibrium is a property of genetic data that allows us to parsimoniously describe genotype frequencies in a population. The reasons why Hardy Weinberg equilibrium generally holds, common reasons for deviation from Hardy Weinberg equilibrium, and methods for checking for significant deviations from Hardy-Weinberg equilibrium will all be discussed.

== Slides ==

[[Media:666.2017.02 - Hardy Weinberg Equilibrium.pdf|Slides in PDF format]]

[[Media:666.02.pdf‎|Previous version]]

== Background Reading ==

Please read the following paper:

Wigginton JE, Cutler DJ and Abecasis GR (2005). A note on exact tests of Hardy-Weinberg equilibrium. ''Am J Hum Genet'' '''76''':887-93
[http://www.sph.umich.edu/csg/abecasis/publications/15789306.html Abstract and PDF]