Changes

== Objective ==

== Objective ==

The objective of this lecture is to introduce the concept of Hardy Weinberg equilibrium. Hardy Weinberg equilibrium is a property of genetic data that allows us to parsimoniously describe genotype frequencies in a population. The reasons why Hardy Weinberg equilibrium generally holds, common reasons for deviation from Hardy Weinberg equilibrium, and methods for checking for significant deviations from Hardy-Weinberg equilibrium.

The objective of this lecture is to introduce the concept of Hardy Weinberg equilibrium. Hardy Weinberg equilibrium is a property of genetic data that allows us to parsimoniously describe genotype frequencies in a population. The reasons why Hardy Weinberg equilibrium generally holds, common reasons for deviation from Hardy Weinberg equilibrium, and methods for checking for significant deviations from Hardy-Weinberg equilibrium will all be discussed.

== Slides ==

== Slides ==

[[Media:666.02.pdf‎|Slides in PDF Format]]

[[Media:666.2017.02 - Hardy Weinberg Equilibrium.pdf|Slides in PDF format]]

 

[[Media:666.02.pdf‎|Previous version]]

== Background Reading ==

== Background Reading ==

Wigginton JE, Cutler DJ and Abecasis GR (2005). A note on exact tests of Hardy-Weinberg equilibrium. ''Am J Hum Genet'' '''76''':887-93

Wigginton JE, Cutler DJ and Abecasis GR (2005). A note on exact tests of Hardy-Weinberg equilibrium. ''Am J Hum Genet'' '''76''':887-93