Difference between revisions of "Biostatistics 666: Hardy-Weinberg Equilibrium"

From Genome Analysis Wiki
Jump to: navigation, search
(Background Reading)
Line 5: Line 5:
== Slides ==
== Slides ==
[[Media:666.02.pdf‎|Slides in PDF Format]]
[[Media:666.2017.02 - Hardy Weinberg Equilibrium.pdf|Slides in PDF format]]
[[Media:666.02.pdf‎|Previous version]]
== Background Reading ==
== Background Reading ==

Latest revision as of 08:30, 11 September 2017


The objective of this lecture is to introduce the concept of Hardy Weinberg equilibrium. Hardy Weinberg equilibrium is a property of genetic data that allows us to parsimoniously describe genotype frequencies in a population. The reasons why Hardy Weinberg equilibrium generally holds, common reasons for deviation from Hardy Weinberg equilibrium, and methods for checking for significant deviations from Hardy-Weinberg equilibrium will all be discussed.


Slides in PDF format

Previous version

Background Reading

Please read the following paper:

Wigginton JE, Cutler DJ and Abecasis GR (2005). A note on exact tests of Hardy-Weinberg equilibrium. Am J Hum Genet 76:887-93 Abstract and PDF