Difference between revisions of "Biostatistics 666: Introduction to De Novo Assembly"

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(Recommended Reading)
(Slides)
 
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== Slides ==
 
== Slides ==
  
[[Media:666.2012.01.pdf|Slides in PDF Format]]
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[[Media:666.2012.01_-_De_Novo_Assembly.pdf|Slides in PDF Format]]
  
 
== Recommended Reading ==
 
== Recommended Reading ==

Latest revision as of 03:38, 4 December 2017

Overview

Introduces the issues surrounding de novo assembly of complex genomes, with a particular focus on issues related to variant discovery. Also provides a brief overview of the results of Lander and Waterman on contig length.

Slides

Slides in PDF Format

Recommended Reading

Iqbal Z, Caccamo M, Turner I, Flicek P, McVean G (2012) De novo assembly and genotyping of variants using colored de Bruijn graphs. Nature Genetics 44:226-232

Lander E and Waterman M (1988) Genomic mapping by fingerprinting random clones: a mathematical analysis. Genomics 2:231-239