Difference between revisions of "Biostatistics 666: Introduction to De Novo Assembly"
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== Slides == | == Slides == | ||
| − | [[Media:666.2012. | + | [[Media:666.2012.01_-_De_Novo_Assembly.pdf|Slides in PDF Format]] |
== Recommended Reading == | == Recommended Reading == | ||
Latest revision as of 03:38, 4 December 2017
Overview
Introduces the issues surrounding de novo assembly of complex genomes, with a particular focus on issues related to variant discovery. Also provides a brief overview of the results of Lander and Waterman on contig length.
Slides
Recommended Reading
Iqbal Z, Caccamo M, Turner I, Flicek P, McVean G (2012) De novo assembly and genotyping of variants using colored de Bruijn graphs. Nature Genetics 44:226-232
Lander E and Waterman M (1988) Genomic mapping by fingerprinting random clones: a mathematical analysis. Genomics 2:231-239
