Difference between revisions of "Biostatistics 666: Introduction to De Novo Assembly"
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Iqbal Z, Caccamo M, Turner I, Flicek P, McVean G (2012) De novo assembly and genotyping of variants using colored de Bruijn graphs. ''Nature Genetics'' '''44''':226-232 | Iqbal Z, Caccamo M, Turner I, Flicek P, McVean G (2012) De novo assembly and genotyping of variants using colored de Bruijn graphs. ''Nature Genetics'' '''44''':226-232 | ||
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| + | Lander E and Waterman M (1988) Genomic mapping by fingerprinting random clones: a mathematical analysis. ''Genomics'' '''2''':231-239 | ||
Revision as of 04:46, 3 December 2012
Overview
Introduces the issues surrounding de novo assembly of complex genomes, with a particular focus on issues related to variant discovery. Also provides a brief overview of the results of Lander and Waterman on contig length.
Slides
Recommended Reading
Iqbal Z, Caccamo M, Turner I, Flicek P, McVean G (2012) De novo assembly and genotyping of variants using colored de Bruijn graphs. Nature Genetics 44:226-232
Lander E and Waterman M (1988) Genomic mapping by fingerprinting random clones: a mathematical analysis. Genomics 2:231-239
