Difference between revisions of "Biostatistics 666: Introduction to the E-M Algorithm"
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== Slides == | == Slides == | ||
− | [[Media:666.10.pdf| | + | [[Media:666.10.pdf|Slides in PDF Format]] |
== Recommended Reading == | == Recommended Reading == | ||
Slatkin M, Excoffier L (1996) Testing for linkage disequilibrium in genotypic data using the EM algorithm. ''Heredity'' '''76''':377–383 | Slatkin M, Excoffier L (1996) Testing for linkage disequilibrium in genotypic data using the EM algorithm. ''Heredity'' '''76''':377–383 |
Revision as of 03:54, 7 October 2010
Objective
Introduce the E-M algorithm in genetics, demonstrating applications to allele frequency estimation for recessive alleles and ABO blood group alleles. After the lecture, students should start to develop an intuition for how the E-M algorithm handles missing data.
Slides
Recommended Reading
Slatkin M, Excoffier L (1996) Testing for linkage disequilibrium in genotypic data using the EM algorithm. Heredity 76:377–383