Difference between revisions of "Biostatistics 666: Introduction to the E-M Algorithm"

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(Slides)
(Slides)
 
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== Slides ==
 
== Slides ==
  
[[Media:666.10.pdf|Slides in PDF Format]]
+
[[Media:666.2017.08 - The E-M Algorithm.pdf|Slides in PDF Format]]
  
 
== Recommended Reading ==
 
== Recommended Reading ==
  
 
Slatkin M, Excoffier L (1996) Testing for linkage disequilibrium in genotypic data using the EM algorithm. ''Heredity''  '''76''':377–383
 
Slatkin M, Excoffier L (1996) Testing for linkage disequilibrium in genotypic data using the EM algorithm. ''Heredity''  '''76''':377–383

Latest revision as of 07:12, 4 October 2017

Objective

Introduce the E-M algorithm in genetics, demonstrating applications to allele frequency estimation for recessive alleles and ABO blood group alleles. After the lecture, students should start to develop an intuition for how the E-M algorithm handles missing data.

Slides

Slides in PDF Format

Recommended Reading

Slatkin M, Excoffier L (1996) Testing for linkage disequilibrium in genotypic data using the EM algorithm. Heredity 76:377–383