Difference between revisions of "Biostatistics 666: Modeling Variation in the Coalescent"
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Revision as of 02:20, 26 January 2010
Objective
This class builds on previous descriptions of the coalescent. In the class we model the impact of mutations on the coalescent and use it to study:
- What is the expected frequency spectrum of neutral variants?
- What is the distribution of S, the expected number variants discovered, after sequencing N samples.
