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Biostatistics 666: Relationship Checking

Objective

Introduce the idea that checking genetic relationships is a critical part of genetic studies. Discuss different approaches for checking genetic relationships and extend our multipoint analysis framework to allow for different types of relative pairs.

Slides

Recommended Reading

  • Boehnke and Cox (1997) Am J Hum Genet 61:423-429
  • Broman and Weber (1998) AJHG 63:1563-4
  • McPeek and Sun (2000) AJHG 66:1076-94
  • Epstein et al. (2000) AJHG 67:1219-31