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Biostatistics 666: Variance Component Analyses

Objective

Introduce the principles of variance component analysis. Introduce kinship coefficients.

Lecture Notes

References

Amos (1994) Am J Hum Genet 54:535-543

Hopper and Matthews (1982) Ann Hum Genet 46:373–383

Lange and Boehnke (1983) Am J Med Genet 14:513-24