Many data sets consist of individuals from different populations, in the cases of structured populations,
this usually result in an increased number of homozygotes.
The inbreeding coefficient FIC is a measure of deviation away from the Hardy Weinberg Equilibrium.
A value of 0 implies no deviation, a negative value implies an excess of heterozygotes and a positive value implies an excess of homozygotes.
The following equation gives the estimate of F where the observed genotypes are available.
The following equation gives the estimate of F where genotype likelihoods are available.
where:
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