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All the above commands will let you do family-based association analysis using kinship matrices generated using pedigree structure coded in pedigree file. The following command lines show examples of using genotype to estimate empirical relationship matrix to do the work.
All the above commands will let you do family-based association analysis using kinship matrices generated using pedigree structure coded in pedigree file. The following command lines show examples of using genotype to estimate empirical relationship matrix to do the work.
./famrvtest --ped your.ped --dat your.dat --SingleVarScore --inverseNormal --useCovariates --traitName LDL --kinGeno
./famrvtest --ped your.ped --dat your.dat --SingleVarScore --inverseNormal --useCovariates --traitName LDL --kinPedigree
===Gene-level Association===
===Gene-level Association===
