Difference between revisions of "Fst"
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Where: | Where: | ||
− | :<math>overline{p} = (p_1 + p_2) / 2</math> | + | :<math>\overline{p} = (p_1 + p_2) / 2</math> |
== References == | == References == |
Latest revision as of 03:47, 3 October 2010
Fst is a measure of population divergence. It measures the reduction in heterozygosity in a subdivided population compared to that in large, random mating population with the same allele frequencies.
Formulae
For the simple case of two populations, this is simply:
Where:
References
Nielsen R, Mountain JL, Huelsenbeck JP and Slatkin M (1998) Maximum-Likelihood Estimation of Population Divergence Times and Population Phylogeny in Models Without Mutation. Evolution 52:669-677
Reynolds J, Weir BS and Cockerham CC (1983) Estimation of the coancestry coefficient: basis for a short-term genetic distance. Genetics 105:767-779.