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Karma uses an existing reference to align short reads, such as those generated by Illumina sequencers.
Karma uses an existing reference to align short reads, such as those generated by Illumina sequencers.
Primary features:
# High performance, high sensitivity
# Large and small gap detection by default
# Multiple gaps per read by default
# Single or paired end reads
# No read length limit
# Quality scores are used to assess quality of maps
# All potential locations are examined exhaustively, none are omitted
# Reasonable memory per CPU ratio on high core count machines
The current version, 0.9.0, is optimized to rapidly map base space reads from Illumina sequencers.
The current version, 0.9.0, is optimized to rapidly map base space reads from Illumina sequencers.
