LASER is xxxx. To use LASER, please read part1 and part2. Also example will guide you through a complete procedure of how to use laser to infer ancestry. If you have feedbacks, please see contact.
Part 1: Prepare data
Use samtools pileup
Use pileup2laser.py script
NOTE: you genotype should be forward strand, mapping quality filter and base quality filter should be appropriately set up.
Tip: You can generate summary of coverage files using scripts.
Part 2: Procrustes analysis
You will need to download software from Chaonglong...
How to interpret your sults
You results will be output as xxx. An example of outputs are like below
We provide a toy example (downloadble from: xxx) The workflow of LASER analysis are explained step by step.
1. generate pileup
2. prepare laser input
3. run laser
Xiaowei Zhan (for data preparation)
Chaolong Wang (for using Laser and interpreting results)