METAL GENOMICCONTROL

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The GENOMICCONTROL setting defaults to off, which means that no correction is applied to input studies. Setting GENOMICCONTROL ON requests that METAL should automatically calculate and apply an appropriate genomic control correction to each study.

Newer versions of METAL also now allow for a specific genomic control parameter as input. In this case, instead of automatically calculating the GENOMICCONTROL value based on available data, METAL will apply the correction according to a user-specified parameter. This option is convenient when full genome scan results are not included in METAL input files.

Example:

   GENOMICCONTROL 1.1