Difference between revisions of "MaCH"
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− | '''MaCH''' (MArkov Chain Haplotyping) is a | + | '''MaCH''' (MArkov Chain Haplotyping) is a Hidden Markov Model (HMM) based haplotyper that reconstructs haplotypes from genotypes of unrelated individuals. Three primary utilities of MaCH are (1) to resolve haplotypes from diploid genotypes; (2) impute missing genotypes; and (3) perform disease mapping analysis. |
== Options == | == Options == | ||
+ | Input Files: | ||
+ | --datfile | ||
+ | Marker information file as described in section 3. | ||
+ | --pedfile | ||
+ | Pedigree file as described in section 3. | ||
+ | |||
== FAQ == | == FAQ == |
Revision as of 17:26, 26 April 2010
MaCH (MArkov Chain Haplotyping) is a Hidden Markov Model (HMM) based haplotyper that reconstructs haplotypes from genotypes of unrelated individuals. Three primary utilities of MaCH are (1) to resolve haplotypes from diploid genotypes; (2) impute missing genotypes; and (3) perform disease mapping analysis.
Options
Input Files: --datfile Marker information file as described in section 3. --pedfile Pedigree file as described in section 3.