MaCH

MaCH (MArkov Chain Haplotyping) is a Hidden Markov Model (HMM) based haplotyper that reconstructs haplotypes from genotypes of unrelated individuals. Three primary utilities of MaCH are (1) to resolve haplotypes from diploid genotypes; (2) impute missing genotypes; and (3) perform disease mapping analysis.

Options

Input Files: --datfile Marker information file for subjects under study. --pedfile Pedigree file for subjects under study.