Difference between revisions of "RAREFY DOCUMENTATION"
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==SOFTWARE INTERFACE== | ==SOFTWARE INTERFACE== | ||
+ | |||
+ | Options: | ||
+ | Input Files : --ped [], --dat [] | ||
+ | Methods : --MCMC, --traitIncreasing, --traitDecreasing | ||
+ | Trait : --inverseNormal, --logTransform, --useCovariates, | ||
+ | --traitName [] | ||
+ | Parameters : --maf [1.0e-03], --effect [2.00] | ||
+ | MCMC : --seed, --chains [3], --iterations [50000000] | ||
+ | Other : --famList [], --famID [], --cpus [5], --prefix [] | ||
==EXAMPLES== | ==EXAMPLES== |
Revision as of 15:13, 3 February 2015
KEY FEATURES
- RAREFY is a likelihood-based method to prioritize individuals in family samples and population samples.
- RAREFY takes account familial relatedness and allows adjusting covariates.
- RAREFY is able to handle large and complex pedigrees.
INPUT FILE FORMAT
- RAREFY takes MERLIN format PED/DAT files as input, no MAP file is needed.
- Input files should have pedigree information, phenotype, and covariates information (if covariates are to be adjusted) saved.
SOFTWARE INTERFACE
Options:
Input Files : --ped [], --dat [] Methods : --MCMC, --traitIncreasing, --traitDecreasing Trait : --inverseNormal, --logTransform, --useCovariates, --traitName [] Parameters : --maf [1.0e-03], --effect [2.00] MCMC : --seed, --chains [3], --iterations [50000000] Other : --famList [], --famID [], --cpus [5], --prefix []