Changes

* In the file with summary statistics named prefix.traitName.singlevar.score.txt contains summary statistics that are needed by Rare-Metal. An example is shown in below:

* In the file with summary statistics named prefix.traitName.singlevar.score.txt contains summary statistics that are needed by Rare-Metal. An example is shown in below:

  LDL mean= -0.00, variance=  1.00, heritability= 34.30

LDL mean= -0.00, variance=  1.00, heritability= 34.30  

  CHR     POS     REF_ALLELE     ALT_ALLELE     INFORMATIVE_N   FOUNDER_AF     ALL_AF  INFORMATIVE_AC  HWE_PVALUE      STAT   ALT_ALLELE_EFFSIZE     PVALUE

CHR       POS REF_ALLELE ALT_ALLELE INFORMATIVE_N FOUNDER_AF   ALL_AF  INFORMATIVE_AC  HWE_PVALUE      STAT ALT_ALLELE_EFFSIZE       PVALUE

   10   45410002       G       A       6103    0.0341589      0.0341589      410     0.165893       126.205 0.309798       4.03074e-10

   10 45410002         G         A           6103    0.034159  0.034159            410   0.165893 126.2050            0.309798 4.030740e-10

   19   45412079       G       A       6103    0.0368124      0.0368124      434     0.714645       -265.84 -0.587356       7.87851e-36

   19 45412079         G         A           6103    0.036812  0.036812            434   0.714645 -265.8400          -0.587356 7.878510e-36

   19   45414451       G       A       6103    0.444989       0.444989       5312    0.0759271      -26.1212       -0.00837122    0.640058

   19 45414451         G         A           6103    0.444989 0.444989           5312    0.075927  -26.1212           -0.008371  6.400580e-01

 

* pvalues from the above output are from the family-based single variant score test.

* pvalues from the above output are from the family-based single variant score test.