Changes

From Genome Analysis Wiki
Jump to navigationJump to search
38 bytes added ,  12:12, 14 April 2014
Line 117: Line 117:     
==== VCF File ====
 
==== VCF File ====
 +
=====GENOTYPES=====
 
* Another option is to use VCF as input. Please refer to the following link for VCF file specification: [[http://www.1000genomes.org/wiki/Analysis/Variant%20Call%20Format/vcf-variant-call-format-version-41 1000 genome wiki VCF specs]]  
 
* Another option is to use VCF as input. Please refer to the following link for VCF file specification: [[http://www.1000genomes.org/wiki/Analysis/Variant%20Call%20Format/vcf-variant-call-format-version-41 1000 genome wiki VCF specs]]  
 
* VCF file should be compressed by bgzip and indexed by tabix, using the following command:
 
* VCF file should be compressed by bgzip and indexed by tabix, using the following command:
Line 129: Line 130:  
* When genotypes are saved in the PED file, the VCF file is not needed. An example command line might look like this:
 
* When genotypes are saved in the PED file, the VCF file is not needed. An example command line might look like this:
 
   --ped input.ped --dat input.dat
 
   --ped input.ped --dat input.dat
 +
 +
=====DOSAGE=====
 
* If you want to analyze dosage data from VCF file, the following option has to be specified: --dosage. A key word "DS" in FORMAT field in VCF file has to included accordingly. An example is in the following:
 
* If you want to analyze dosage data from VCF file, the following option has to be specified: --dosage. A key word "DS" in FORMAT field in VCF file has to included accordingly. An example is in the following:
  
2,004

edits

Navigation menu