Difference between revisions of "RAREMETALWORKER METHOD"
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== Modeling Relatedness == | == Modeling Relatedness == | ||
+ | we use a variance component model to handle familial relationships. | ||
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+ | == Single Variant Score Tests == | ||
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+ | == Summary Statistics == | ||
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+ | == Covariance Matrices == |
Revision as of 12:59, 10 March 2014
Brief Introduction
RAREMETALWORKER(RMW) generates single variant association results from score test, together with summary statistics and covariance matrices of the score statistics.
In the following sections, we will go through the methods behind RWM including statistic model, handling sample relatedness, and definitions of statistics in the output.
Modeling Relatedness
we use a variance component model to handle familial relationships.