Changes

* According to the example above, PCSK9 had a p-value of 7.54587e-11 from the gene-based burden test, where three variants from this gene were included. Another hit from this meta analysis is APOE, where only one variant was included in the burden test.

* According to the example above, PCSK9 had a p-value of 7.54587e-11 from the gene-based burden test, where three variants from this gene were included. Another hit from this meta analysis is APOE, where only one variant was included in the burden test.

==== QQ PLOTS and MANHATTAN PLOTS ====

==== PLOTS ====

'''rareMETAL''' generates QQ plots and manhattan plots from single variant and gene-level meta-analysis by default. Example QQ plots and manhattan plots are:

'''rareMETAL''' generates QQ plots and manhattan plots from single variant and gene-level meta-analysis by default. Example QQ plots and manhattan plots are:

{| border="1" cellpadding="5" cellspacing="0" align="center"

{| border="1" cellpadding="5" cellspacing="0" align="center"

| align="center" width="200" | [[File:burden.manhattan.png]]

| align="center" width="200" | [[File:burden.manhattan.png]]

|}

|}

==== Log File ====

==== Log File ====