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! scope="col" width="120pt" | Test
 
! scope="col" width="120pt" | Test
 
! scope="col" width="50pt" | Statistics
 
! scope="col" width="50pt" | Statistics
! scope="col" width="225pt" | Null Distribution
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! scope="col" width="225pt" | Null Distribution | Notation
 
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| Single Variant      || <math>T=\sum_{i=1}^n {U_i}\bigg/\sqrt{\sum_{i=1}^n{V_i}}</math> || <math>T\sim\mathbf{N}(0,1)</math>
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| Single Variant      || <math>T=\sum_{i=1}^n {U_i}\bigg/\sqrt{\sum_{i=1}^n{V_i}}</math> || <math>T\sim\mathbf{N}(0,1)</math> || <math> U_i \text{is the score statistic from study i; } V_i \text{is the variance of } U_i<\math>
 
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| un-weighted Burden      || <math>T_b=\sum_{i=1}^n{\mathbf{U_i}}\Big/\sqrt{\sum_{i=1}^n{\mathbf{V_i}}}</math> || <math>T_b\sim\mathbf{N}(0,1)</math>
 
| un-weighted Burden      || <math>T_b=\sum_{i=1}^n{\mathbf{U_i}}\Big/\sqrt{\sum_{i=1}^n{\mathbf{V_i}}}</math> || <math>T_b\sim\mathbf{N}(0,1)</math>
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