Changes

<math>U_{i,k} </math> is the score statistic for the <math>i^{th} </math> variant from the <math> k^{th} </math> study  

<math>U_{i,k} </math> is the score statistic for the <math>i^{th} </math> variant from the <math> k^{th} </math> study  

<math>\mathbf{U_k}</math> is the vector of score statistics of rare variants in a gene from the <math> k^{th} </math> study.

<math>\mathbf{U_k}</math> is the vector of score statistics of rare variants in a gene from the <math> k^{th} </math> study.

<math>V_{ij,k} </math> is the covariance of the score statistics between the <math>i^{th} </math> and the <math>j^{th} </math> variant from the <math> k^{th} </math> study

<math>\mathbf{V_k}</math> is the variance-covariance matrix of score statistics of rare variants in a gene from the <math> k^{th} </math> study, or <math>\mathbf{V_k} = cov(\mathbf{U_k})</math>

<math> S </math> is the number of studies

<math> S </math> is the number of studies