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, 21:34, 8 April 2014
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| <math>U_{i,k} </math> is the score statistic for the <math>i^{th} </math> variant from the <math> k^{th} </math> study | | <math>U_{i,k} </math> is the score statistic for the <math>i^{th} </math> variant from the <math> k^{th} </math> study |
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| + | <math>V_{ij,k} </math> is the covariance of the score statistics between the <math>i^{th} </math> and the <math>j^{th} </math> variant from the <math> k^{th} </math> study |
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| <math>\mathbf{U_k}</math> is the vector of score statistics of rare variants in a gene from the <math> k^{th} </math> study. | | <math>\mathbf{U_k}</math> is the vector of score statistics of rare variants in a gene from the <math> k^{th} </math> study. |
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− | <math>V_{ij,k} </math> is the covariance of the score statistics between the <math>i^{th} </math> and the <math>j^{th} </math> variant from the <math> k^{th} </math> study | + | <math>\mathbf{V_k}</math> is the variance-covariance matrix of score statistics of rare variants in a gene from the <math> k^{th} </math> study, or <math>\mathbf{V_k} = cov(\mathbf{U_k})</math> |
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| <math> S </math> is the number of studies | | <math> S </math> is the number of studies |