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** callrate.cutoff specifies the call rate cutoffs that will be used. All sites with call rates lower than the cutoff will be labelled as missing.  
 
** callrate.cutoff specifies the call rate cutoffs that will be used. All sites with call rates lower than the cutoff will be labelled as missing.  
 
** hwe.cutoff specifies the cutoffs for call rate, All sites with call rate lower than the cutoff will be labeled as missing.     
 
** hwe.cutoff specifies the cutoffs for call rate, All sites with call rate lower than the cutoff will be labeled as missing.     
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* Output is a dataframe that consist of the following fields:
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** pos: Variant physical position
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** ref: Reference allele
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** alt: Alternative allele
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** no.sample: Number of samples
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** p.value: P-values
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** statistic: Test statistic (score statistic)
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** maf: Minor allele frequency
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** beta1.est: Beta estimates
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** beta1.sd: The standard deviation for beta estimates
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** hsq.est: Locus genetic variance estimates                                                 
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** direction.by.study: Direction of genetic effects by study
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** anno: Annotation for variants
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== Performing gene level association test ==
 
== Performing gene level association test ==
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