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== Perform single variant association test using a group file ==
== Perform single variant association test using a group file ==
Summary level statistics collected in meta-analysis can often be messy, messier for lower frequency variants than for common variants. To correct for the right alleles, and make sure that ref/alt alleles from each study are properly aligned, it is often desirable to
Summary level statistics collected in meta-analysis can often be messy, messier for lower frequency variants than for common variants. To correct for the right alleles, and make sure that ref/alt alleles from each study are properly aligned, it is often desirable to specify a group file. To do so, our function rareMETALS.single.group can be used. See the R help for details.
== Perform gene-level test with a group file ==
== Perform gene-level test with a group file ==
Similar to single variant analysis, it is often desirable to use a group file to properly align alleles across different studies. To do so, please use our function == Perform single variant association test using a group file ==
Summary level statistics collected in meta-analysis can often be messy, messier for lower frequency variants than for common variants. To correct for the right alleles, and make sure that ref/alt alleles from each study are properly aligned, it is often desirable to specify a group file. To do so, our function rareMETALS.range.group can be used. See R help for details.
