Raremetal Incoming updates

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Revision as of 17:55, 16 March 2018 by Abought (talk | contribs)
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Incoming update

  • Add an option to store group file from vcf
  • Take snpeff as annotation input
  • When no conditional variant is available, warning is generated but not written to log file.
  • enable reading from .gz annotated vcf
  • add SKAT-O
  • solve the numeric issue of lambda = 0 in SKAT
  • In conditional analysis, when cov matrix between the test variant and its conditioned variants is not invertible, MathSVD still tries to invert that matrix and that leads to weird conditional p values.
  • Optimization for binary traits
  • Memory optimization for gene-based test in large panel