Read Mapping
From Genome Analysis Wiki
Jump to navigationJump to searchRead mappers that we like are
Karma - Currently under development here in Michigan; trades memory for speed, but is both fast and sensitive (now matches or exceeds both bwa and NovoAlign), and highly effective on nodes with high core counts.
BWA - A fast aligner developed by Richard Durbin and Heng Li.
NovoAlign - Potentially, a much more sensitive, but slow, aligner.
All of these should output SAM format.
Other Aligners
MAQ - The venerable short read aligner developed by Richard Durbin and Heng Li.
