Difference between revisions of "SEQMIX"

From Genome Analysis Wiki
Jump to navigationJump to search
Line 9: Line 9:
 
== Download ==
 
== Download ==
  
(Coming soon)
+
[[SEQMIX_0.1.tar]]
  
 
== Related Programs ==
 
== Related Programs ==

Revision as of 02:46, 4 November 2013

Overview

SEQMIX is a C++ program that takes advantage of off-targeted sequence reads from exome/targeted sequencing experiments for accurate local ancestry inference.

Method

Before running SEQMIX, it is important to LD prune your data so that pairs of sites in high LD (r^2 > 0.1) are identified and only the one with a higher sequence depth are included into the model. As the sequence depth distribution is sample dependent, it is necessary to prune the sequence data for each individual.

Download

SEQMIX_0.1.tar

Related Programs

Local ancestry inference with high density genotype array data can be done with existing software HAPMIX, LAMP, ANCESTRYMAP.

Whole genome ancestry inference with ultra low coverage sequence data can be analyzed with LASER.