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*[[Rarefy|'''rarefy''']] is a C++ tool to facilitate sequencing study design using family samples by selecting informative families and individuals from a sample. It takes account pedigree structure and calculates an informative score for each individual to evaluate the potential of carrying trait-influencing rare variants. Rarefy has been used for selecting individuals in Minnesota Twins substance abuse whole-genome sequencing project and SardiNia deep sequencing project.
*[[Rarefy|'''rarefy''']] is a C++ tool to facilitate sequencing study design using family samples by selecting informative families and individuals from a sample. It takes account pedigree structure and calculates an informative score for each individual to evaluate the potential of carrying trait-influencing rare variants. Rarefy has been used for selecting individuals in Minnesota Twins substance abuse whole-genome sequencing project and SardiNia deep sequencing project.
*[[FamRvTest|'''famRvTest''']] is an efficient C++ tool for rare variant association analysis using a linear-mixed model approach. It handles population structure, familial relatedness and study-specific covariates. The tool supports both single variant and gene-level associations with various methods implemented. It has been used in eQTL and quantitative traits association analyses in T2Dgenes project.
*[[Famrvtest|'''famrvtest''']] is an efficient C++ tool for rare variant association analysis using a linear-mixed model approach. It handles population structure, familial relatedness and study-specific covariates. The tool supports both single variant and gene-level associations with various methods implemented. It has been used in eQTL and quantitative traits association analyses in T2Dgenes project.
*[[RAREMETALWORKER|'''RAREMETALWORKER''']] is a C++ tool to generate summary statistics for meta-analysis of rare variants using raremetal. FamRvTest handles both related and unrelated individuals. It has been used in tens of research centers and institutions around the world since its first release in 2012.
*[[RAREMETALWORKER|'''RAREMETALWORKER''']] is a C++ tool to generate summary statistics for meta-analysis of rare variants using raremetal. FamRvTest handles both related and unrelated individuals. It has been used in tens of research centers and institutions around the world since its first release in 2012.
*[[RAREMETAL|'''RAREMETAL''']] is a C++ tool for meta-analysis of rare variants. Raremetal supports both single variant and gene-level tests. It is currently being used in Exomechip blood lipids consortium meta-analyses and [[EMADS|EMADS]] project.
*[[RAREMETAL|'''RAREMETAL''']] is a C++ tool for meta-analysis of rare variants. Raremetal supports both single variant and gene-level tests. It is currently being used in Exomechip blood lipids consortium meta-analyses and [[EMADS|EMADS]] project.
