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# Changes

→Here is an example where this normalization algorithm fails

Normalization involves reducing representations of a variant to a canonical representation. Normalization can be applied to biallelic variants or multiallelic variants. The problem of normalization is solvable and there exists a unique representation that is left aligned and parsimonious. Mathematical proof is published. [http://bioinformatics.oxfordjournals.org/content/~~early~~suppl/2015/~~03~~02/~~22~~19/~~bioinformatics~~btv112.DC1/VtNormApplicationNote_supp_20141113_1346.~~btv112~~pdf]