From Genome Analysis Wiki
Jump to: navigation, search

Genotype Likelihood based Allele Frequency

227 bytes added, 09:36, 28 July 2015
Estimation of Genotype Frequencies without assuming HWE
where <math>n</math> is the number of alleles. <math>\frac{n(n+1)}{2}</math> is the number of genotypes possible for <math>n</math> alleles. So we are simply starting with equal frequency estimate guesses for each genotype.
The E step equates the expectation of the genotype <math>G_{i,j}</math> for individual k as:

Navigation menu