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| | * Allows conditional analysis to be performed in both gene-level meta-analysis and single variants meta-analysis. | | * Allows conditional analysis to be performed in both gene-level meta-analysis and single variants meta-analysis. |
| | * Generate QQ plots and manhattan plots by default. | | * Generate QQ plots and manhattan plots by default. |
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| − | == Brief Description ==
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| − | '''RAREMETAL''' is a computationally efficient tool for meta-analysis of rare variants using sequencing or genotyping array data. '''RAREMETAL''' takes summary statistics and LD matrices generated by [[Rare-Metal-Worker|'''RAREMETALWORKER''']] or [http://genome.sph.umich.edu/wiki/Rvtests '''rvtests'''], handles related and unrelated individuals, and supports both single variant and burden meta-analysis. '''RAREMETAL''' generates high quality plots by default and has options that allow users to build reports at different levels.
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| − | '''RAREMETAL''' is developed by Shuang Feng, Dajiang Liu and Gonçalo Abecasis. A R-package written by Dajiang Liu using the same methodology is [[RareMetals|'''available''']].
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| | == Approach == | | == Approach == |
