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, 12:16, 29 July 2013
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| * We provide functions for performing single variant conditional meta-analysis. For variants within the sliding window, the conditional analysis is exact, in the sense that they are equal to conditional analysis results obtained using individual level data. | | * We provide functions for performing single variant conditional meta-analysis. For variants within the sliding window, the conditional analysis is exact, in the sense that they are equal to conditional analysis results obtained using individual level data. |
| * The following function can be used: | | * The following function can be used: |
− | conditional.rareMETALS.single.basic(candidate.variant,score.stat.file,cov.file,known.variant.vec,maf.cutoff,no.boot=0,alternative=c('two.sided','greater','less'),alpha=0.05,ix.gold=1,out.digits=4,callrate.cutoff=0,hwe.cutoff=0,gene.file="refFlat_hg19.txt.gz",p.value.known.variant.vec="N/A",anno.known.variant.vec="N/A",anno.candidate.variant="N/A") | + | conditional.rareMETALS.single.basic(candidate.variant,score.stat.file,cov.file,known.variant.vec,maf.cutoff,no.boot=0,alternative=c('two.sided','greater','less'), |
| + | alpha=0.05,ix.gold=1,out.digits=4,callrate.cutoff=0,hwe.cutoff=0,gene.file="refFlat_hg19.txt.gz",p.value.known.variant.vec="N/A", |
| + | anno.known.variant.vec="N/A",anno.candidate.variant="N/A") |
| | | |
| * Input parameters are described below: | | * Input parameters are described below: |