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28 bytes added ,  21:57, 8 April 2014
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===BURDEN META ANALYSIS===
 
===BURDEN META ANALYSIS===
Meta-analysis burden score test statistics for a gene can be reconstructed  
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Once single variant meta analysis statistics are constructed, burden test score statistic can be reconstructed from these
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<math>T_{meta,b}=\mathbf{w^T}\sum_{k=1}^S{\mathbf{U_k}}\bigg/\sqrt{\mathbf{w^T}\left(\sum_{k=1}^S{\mathbf{V_k}}\right)\mathbf{w}}</math>
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<math>T_{meta,b}=\mathbf{w^TU_{meta}}\bigg/\sqrt{\mathbf{w^T}\left(\sum_{k=1}^S{\mathbf{V_k}}\right)\mathbf{w}}</math>
    
===VT META ANALYSIS===
 
===VT META ANALYSIS===
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