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28 bytes added
, 21:57, 8 April 2014
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| ===BURDEN META ANALYSIS=== | | ===BURDEN META ANALYSIS=== |
− | Meta-analysis burden score test statistics for a gene can be reconstructed
| + | Once single variant meta analysis statistics are constructed, burden test score statistic can be reconstructed from these |
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− | <math>T_{meta,b}=\mathbf{w^T}\sum_{k=1}^S{\mathbf{U_k}}\bigg/\sqrt{\mathbf{w^T}\left(\sum_{k=1}^S{\mathbf{V_k}}\right)\mathbf{w}}</math> | + | <math>T_{meta,b}=\mathbf{w^TU_{meta}}\bigg/\sqrt{\mathbf{w^T}\left(\sum_{k=1}^S{\mathbf{V_k}}\right)\mathbf{w}}</math> |
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| ===VT META ANALYSIS=== | | ===VT META ANALYSIS=== |