# Changes

## RAREMETAL METHOD

, 22:19, 8 April 2014
SKAT META ANALYSIS
As shown in Wu et. al, the null distribution of the $\mathbf{Q}$ statistic follows a mixture chi-sqaured distribution described as
$\mathbf{Q}\sim\sum_{i=1}^m{\lambda_i\chi_{1,i}^2},$ where $\left(\lambda_1,\lambda_2,\dots,\lambda_m\right)$ are eigen values of $\left(\sum_mathbf{i=1}^nV_{\mathbf{V_imeta}}\right)^\frac{1}{2}}\mathbf{W}\left(\sum_mathbf{i=1}^nV_{\mathbf{V_imeta}}\right)^\frac{1}{2}}$
2,004
edits