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Jump to navigationJump to search→A Simple Tutorial for Using the rareMETALS.single function
rareMETALS.single function allow you to perform meta-analyses for single variant association tests. The summary association statistics are combined using Mantel Haenszel test statistic. The details are described in our method paper Liu et al, Nat Genet, 2014.
rareMETALS.single function allow you to perform meta-analyses for single variant association tests. The summary association statistics are combined using Mantel Haenszel test statistic. The details are described in our method paper Liu et al, Nat Genet, 2014.
Assume that you have a set of single variant score statistics and their covariance matrices. The examplar command can be:
Assume that you have a set of single variant score statistics and their covariance matrices.
Example:
cov.file <- c("study1.MetaCov.assoc.gz","study2.MetaCov.assoc.gz");
cov.file <- c("study1.MetaCov.assoc.gz","study2.MetaCov.assoc.gz");
