Changes

== Key Features ==

== Key Features ==

'''RAREMETAL''' has the following features:

'''RAREMETAL''' has the following features:

* '''RAREMETAL''' performs gene-based or region-based meta analysis using Burden tests with the following methods: CMC_counts, Madsen-Browning, SKAT, and Variable Threshold.  

* Performs gene-based or region-based meta analysis using Burden tests with the following methods: CMC_counts, Madsen-Browning, SKAT, and Variable Threshold.  

* '''RAREMETAL''' performs single variant metal-analysis by default.  

* Performs single variant metal-analysis by default.  

* '''RAREMETAL''' allows customized groups of variants to be tested.

* Allows customized groups of variants to be tested.

* '''RAREMETAL''' allows conditional analysis to be performed in both gene-level meta-analysis and single variants meta-analysis.

* Allows conditional analysis to be performed in both gene-level meta-analysis and single variants meta-analysis.

* '''RAREMETAL''' generate QQ plots and manhattan plots by default.

* Generate QQ plots and manhattan plots by default.

== Brief Description ==

== Brief Description ==